A Non-Enzymatic Method to Obtain a Fat Tissue Derivative Highly Enriched in Adipose Stem Cells (ASCs) from Human Lipoaspirates: Preliminary Results.

Adipose tissue possesses phenotypic gene expression characteristics that are similar to human mesenchymal stem cells (hMSCs). Nevertheless, the multilineage potential may be inhibited, and cells may not expand adequately to satisfy the requirements of Good Manufacturing Practice (cGMP).

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Bio-automatic separator for extracting stromal vascular fraction from adipose tissue.

Stem cells are fascinating and elusive. To study them, researchers initially applied traditional methods, but quickly realized they needs to be adjusted to complied with the features of this new field of research.  This process of technological and methodological innovation continues till today and makes this branch of research very dynamic.

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Use of tissues rich in MSCs in the treatment of diabetic and artheriopatic ulcers of lower limbs.

 

Ulcers represent the heaviest social and economic burden among diabetes complications, being the reason of long follow-up in outpatient services, increased hospitalizations as well as drastic QOI lowering for patients affected. The lifetime risk for a diabetic patient to develop an ulcer is 25%, and the lesion will lead to major or minor amputation in at least 14 % of patients affected. In diabetic artheriopathic patients, the entity of skin ulcers may compromise limb healing and salvage despite the

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Regenerative Surgery applied to hidradenitis suppurativa: what prospects?

The hidradenitis suppurativa is a chronic and recurrent dermatological disease, which can appear after puberty and usually affects the axillary area and / or the genito-femoral area; it has a prevalence of 1-6%, mainly affects women and has a negative impact on quality of life. The common therapies have always given unsatisfactory results, but recently it can propose  more effective treatments, both medical and surgical.

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