Use of tissues rich in MSCs in the treatment of diabetic and artheriopatic ulcers of lower limbs.
Ulcers represent the heaviest social and economic burden among diabetes complications, being the reason of long follow-up in outpatient services, increased hospitalizations as well as drastic QOI lowering for patients affected. The lifetime risk for a diabetic patient to develop an ulcer is 25%, and the lesion will lead to major or minor amputation in at least 14 % of patients affected. In diabetic artheriopathic patients, the entity of skin ulcers may compromise limb healing and salvage despite the